Yale University

Yale University
Project #:2-U19-AI089992-06A1

Title: Systems Immune Profiling of Divergent Responses to Infection

PI: David Hafler and Ruth Montgomery

Yale University

Primary Projects

Primary Projects

Molecular Profiling of the Immune Response in Lyme Disease

Project Leader: Linda Bockenstedt

Institution: Yale University

Molecular Signatures of West Nile virus susceptibility

Project Leader: Ruth Montgomery

Institution: Yale University

Effects of Age on Cellular, Transcriptomic and Biochemical Influenza Signatures

Project Leader: Albert Shaw

Institution: Yale University

Data Management and Analysis

Project Leader: Steven Kleinstein

Institution: Yale University

Single Cell Phenotyping Core

Project Leader: Ruth Montgomery

Institution: Yale University

Clinical Subjects and Recruitment Core

Project Leader: Albert Shaw

Institution: Yale University

IOF Projects

Identification, standardization and dissemination of HIPC immune signatures

Project Leader: Steven Kleinstein

Institution: Yale University School of Medicine

High-throughput immunophenotypic analyses of humoral responses in Lyme Disease

Project Leader: Linda Bockenstedt

Institution: Yale University

Zika Supplements

Immunologic analysis of maternal samples from the NIAID/NICHD Zika in Infants and Pregnancy (ZIP) program

Project Leader 1: Eva Harris

Institution: University of California, Berkeley

Project Leader 2: Ruth Montgomery

Institution: Yale University

Universal Influenza Vaccine Supplements

Integrated transcriptomics and BCR analyses at the single-cell level to examine the effect of age and functional status on B cell responses to the high dose influenza vaccine

Project Leader: Ruth Montgomery

Institution: Yale University