NIAID Supported Research Resources

NIH Tetramer Core Facility provides MHC class I and class II tetramer reagents to the research community worldwide for use in basic and clinical research (not suitable for Use in Man). Approved users provide peptides for all class I and some class II tetramers and pay all shipping and handling charges. Tetramer production costs are covered by the NIH Tetramer Core Facility.

Biodefense and Emerging Infections Research Resources Repository (BEI Resources) provides reagents, tools, and information for studying Category A, B, and C priority pathogens, emerging infectious disease agents and other biological materials of relevance, including immunological reagents, to the research community. Approved users pay all shipping and handling charges. Reagent production costs are covered by BEI Resources.

Nonhuman Primate Reagent Resource produces and distributes conventional antibodies for nonhuman primate in vitro diagnostics, and primatized recombinant antibodies and fusion proteins for in vivo administration; and disseminates information on assays, experimental techniques, and commercial immunologic reagents.

Immune Epitope Database and Analysis Resource (IEDB) contains antibody and T cell epitopes and related information for infectious and immune-mediated diseases. The Analysis Resource component includes antibody and T cell epitope prediction algorithms, epitope homology/conservancy analysis tools, and epitope visualization tools.

Bioinformatics Resource Centers (BRCs) consist of four centers, each specializing in a different group of pathogens (all bacterial species, all viral families, all eukaryotic pathogen species, and invertebrate vectors of human pathogens). The BRCs provide data, tools, and services such as: annotated genome sequence information; functional genomics, proteomics, metagenomics and other ?-omics? data; basic research and clinical data; analytical resources, bioinformatics tools, and services for data analysis; and experimental protocols.