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About HIPC

The Human Immunology Project Consortium (HIPC) program was established in 2010 by the NIAID Division of Allergy, Immunology, and Transplantation as part of the overall NIAID focus on human immunology. The purpose of HIPC is to capitalize on recent advances in immune profiling methods in order to create a novel public resource that characterizes diverse states of the human immune system following infection; prior to and following vaccination against an infectious disease; or prior to and following treatment with an immune adjuvant that targets a known innate immune receptor(s).

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  • Recent Publications

  • HIPC Technologies

    HIPC investigators utilize cutting edge technologies to define immune signatures in healthy, vaccinated, and diseased states. These technologies include: quantitative gene expression platforms (Illumina, Affymetrix, Nanostring & RNAseq) for innate and adaptive immune response profiling; multiparameter blood cell subset analyses (phenotype & function, including PhosphoFlow); antibody binding/neutralization and repertoire analysis; cytokine and chemokine levels; high throughput HLA, Ig & TCR sequencing; and advanced mass spectrometry methods including highly sensitive epitope identification as well as the CyTOFTM approach, which combines flow cytometry with atomic mass spectrometry for detailed cellular analyses.

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